Event-Related Oscillations in Alcoholism Research: A Review.
نویسندگان
چکیده
Alcohol dependence is characterized as a multi-factorial disorder caused by a complex interaction between genetic and environmental liabilities across development. A variety of neurocognitive deficits/dysfunctions involving impairments in different brain regions and/or neural circuitries have been associated with chronic alcoholism, as well as with a predisposition to develop alcoholism. Several neurobiological and neurobehavioral approaches and methods of analyses have been used to understand the nature of these neurocognitive impairments/deficits in alcoholism. In the present review, we have examined relatively novel methods of analyses of the brain signals that are collectively referred to as event-related oscillations (EROs) and show promise to further our understanding of human brain dynamics while performing various tasks. These new measures of dynamic brain processes have exquisite temporal resolution and allow the study of neural networks underlying responses to sensory and cognitive events, thus providing a closer link to the physiology underlying them. Here, we have reviewed EROs in the study of alcoholism, their usefulness in understanding dynamical brain functions/dysfunctions associated with alcoholism as well as their utility as effective endophenotypes to identify and understand genes associated with both brain oscillations and alcoholism.
منابع مشابه
Event-related oscillations versus event-related potentials in a P300 task as biomarkers for alcoholism.
OBJECTIVE It has been proposed that event-related oscillation (ERO) measures of EEG activity recorded in P300 tasks provide more powerful biomarkers of alcoholism than event-related potential (ERP) measures. This study examines this question in a group of long-term abstinent alcoholics (LTAAs). METHODS EEGs were recorded on 48 LTAAs and 48 age and gender-matched nonalcoholic controls (NACs) d...
متن کاملAlcoholism and human electrophysiology.
Electroencephalography (EEG), the recording of electrical signals from the brain, provides a noninvasive measure of brain function as it is happening. Research using EEG, as well as event-related potentials (ERPs) and event-related oscillations (EROs), which measure brain activity in response to a specific stimulus, have shown that the brain activity of alcoholics and nonalcoholics differs in s...
متن کاملAdvances in Electrophysiological Research
Electrophysiological measures of brain function are effective tools to understand neurocognitive phenomena and sensitive indicators of pathophysiological processes associated with various clinical conditions, including alcoholism. Individuals with alcohol use disorder (AUD) and their high-risk offspring have consistently shown dysfunction in several electrophysiological measures in resting stat...
متن کاملEvent-related oscillations vs. event-related potentials in a P300 task as biomarkers for alcoholism
متن کامل
The utility of neurophysiological markers in the study of alcoholism.
OBJECTIVE This review attempts to differentiate neuroelectric measures (electroencephalogram (EEG), event-related potentials (ERPs) and event-related oscillations (EROs)) related to acute and chronic effects of alcohol on the brain from those that reflect underlying deficits related to the predisposition to develop alcoholism and related disorders. The utility of these neuroelectric measures as...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of addiction research & therapy
دوره Suppl 7 1 شماره
صفحات -
تاریخ انتشار 2012